What Diary of a CEO says about gut health

In their own words

Claims he is 'absolutely convinced' nitric oxide will eradicate and cure Alzheimer's because it addresses every root cause of the disease.
00:00:00Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Says he healed his diabetic, paraplegic father's four-year non-healing wound in six months using topical nitric oxide.
00:09:16Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
States flatly that 'no one is interested in curing human disease because medicine is a business' and the largest economic model in the world.
00:24:05Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Reports a study where seven days of twice-daily mouthwash raised one 21-year-old's blood pressure by 26 mmHg, raising his cardiovascular risk ~26%.
00:45:11Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Claims 100% of solid-tumor cancer patients he sees have a dental infection, and he refers cancer patients to a dentist first.
00:49:35Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Asserts 100% of root-canal teeth are infected dead tissue that nobody would leave anywhere else in the body.
00:51:56Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Says fluoride has 'no benefit and it's all risk,' lowering kids' IQ by up to seven points and acting as a thyroid and neuro toxin.
00:56:14Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Is dismissive of biohacker Brian Johnson's approach and warns against following influencers without science credentials.
00:32:32Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Erectile dysfunction is the first symptom of nitric oxide deficiency, called 'the canary in the coal mine' for cardiovascular disease.
00:05:25Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Two of three Americans have unsafe blood pressure, and 50% on medication don't respond because drugs aren't targeted at nitric oxide.
00:07:04Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
By age 40 we lose ~50% of nitric oxide production; people aged 70-80 can have 75% less than 20-year-olds.
00:16:57Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Nitric oxide supports all three hallmarks of longevity: stem cell mobilization, telomerase activation, and mitochondrial function.
00:31:55Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Humans lack the enzyme to convert dietary nitrate, so we are 100% dependent on oral bacteria to make nitric oxide from food.
00:46:16Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Without the right oral bacteria you get 'zero nitric oxide benefits' from a plant-based diet.
00:47:56Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Using mouthwash can erase the cardioprotective benefits of exercise.
01:00:39Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Nasal breathing and humming activate the nitric oxide enzyme in the sinuses, helping lower blood pressure.
01:14:56Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Many commercial beetroot powders are 'dead beats' containing zero nitrate and were used as placebos in his clinical trials.
01:08:24Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Antacid use roughly quadrupled over 20 years; PPIs block stomach acid needed to absorb B vitamins, magnesium, iron and iodine.
01:11:39Dr. Nathan Bryan · The Diary of a CEO · Apr 2025
Inchauspé claims the more glucose spikes you have, the faster you die and age.
00:00:00Jessie Inchauspé · The Diary of a CEO · May 2023
A 2018 study revealed most people without diabetes still experience daily blood sugar spikes without knowing it.
00:19:11Jessie Inchauspé · The Diary of a CEO · May 2023
Eating food in the right order (veggies, then protein/fat, then starches/sugars) can reduce a meal's glucose spike by up to 75%.
00:49:18Jessie Inchauspé · The Diary of a CEO · May 2023
One tablespoon of vinegar in water before a meal can reduce the glucose spike by up to 20%.
01:09:58Jessie Inchauspé · The Diary of a CEO · May 2023
Glucose spikes are linked to cravings, fatigue, poor sleep, brain fog, acne, aging, Alzheimer's, cancer, infertility and PCOS.
00:33:12Jessie Inchauspé · The Diary of a CEO · May 2023
More insulin raises testosterone in females, driving PCOS symptoms; balancing glucose can reverse it.
00:42:31Jessie Inchauspé · The Diary of a CEO · May 2023
A can of fruit juice contains almost as much sugar as a can of Coca-Cola, with no protective fiber.
01:06:20Jessie Inchauspé · The Diary of a CEO · May 2023
Inchauspé broke her back jumping off a 30-foot waterfall in Hawaii, walking a mile through jungle before realizing the injury.
00:05:08Jessie Inchauspé · The Diary of a CEO · May 2023
Her vertebra was in 13 pieces, requiring surgery with a metal cage and 3-inch nails drilled into her spine.
00:08:45Jessie Inchauspé · The Diary of a CEO · May 2023
Some scientists call Alzheimer's 'type 3 diabetes' because of its tight link to glucose levels.
00:28:01Jessie Inchauspé · The Diary of a CEO · May 2023
Three out of five people in the world will die of an inflammation-based disease.
00:30:37Jessie Inchauspé · The Diary of a CEO · May 2023
Calories were originally measured by burning food and recording how much surrounding water heated up.
00:57:33Jessie Inchauspé · The Diary of a CEO · May 2023
Fiber forms a viscous protective mesh on the intestine wall that slows glucose absorption.
00:53:27Jessie Inchauspé · The Diary of a CEO · May 2023
The soleus muscle in the calf is especially good at soaking up glucose, so calf raises after eating help.
01:13:06Jessie Inchauspé · The Diary of a CEO · May 2023
Sugar releases dopamine, the same pleasure molecule triggered by sex, video games and drugs, making it addictive.
00:23:19Jessie Inchauspé · The Diary of a CEO · May 2023
Inchauspé stresses sugar gives pleasure (dopamine), not real biological energy.
01:21:50Jessie Inchauspé · The Diary of a CEO · May 2023
Claims 30-second all-out sprints burn 40% more fat than even high-intensity interval training.
00:00:09Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Presents MRI thigh slices: a 70-year-old triathlete's muscle is virtually indistinguishable from a 40-year-old's.
00:33:19Dr. Vonda Wright · The Diary of a CEO · Jul 2024
An 80-year-old who lifts weights consistently is functionally as strong as a 60-year-old who doesn't.
00:35:23Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Her study found athletic performance only significantly declines after the mid-70s, not at 50 or 60.
01:27:46Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Old sedentary mice put on a (real, $30,000) treadmill rejuvenated their muscle stem cells in just two weeks.
01:32:54Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Wright reveals she gained 30 lb during menopause and at 47 felt she 'was going to die.'
01:47:23Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Reveals she left a secure academic surgeon role at 57 to bet her own money on private practice.
02:04:32Dr. Vonda Wright · The Diary of a CEO · Jul 2024
UK life expectancy is ~81 and US ~77.6, but average health span is only about 63.
00:06:44Dr. Vonda Wright · The Diary of a CEO · Jul 2024
70-90% of how we age is determined by lifestyle choices, not inherited genes.
00:07:14Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Gaining 1 lb of body weight exerts roughly 9 lb of pressure across the knee joint.
00:57:39Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Pure calorie restriction loses 25-50% of weight as muscle; regained weight is ~80% fat.
01:00:45Dr. Vonda Wright · The Diary of a CEO · Jul 2024
80% of women in perimenopause experience a 'musculoskeletal syndrome of menopause.'
01:37:33Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Frozen shoulder is largely inflammatory and can take up to 2 years to resolve.
01:43:14Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Leucine drives muscle building via mTOR; whey protein is ~10% leucine, meat ~8%, plants ~6.5%.
01:54:39Dr. Vonda Wright · The Diary of a CEO · Jul 2024
The frailty VO2 max line to live independently is ~18 ml/kg/min for men, 16 for women.
01:59:48Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Sedentary 30-year-olds had the lowest levels of the longevity protein Klotho in her study.
01:29:48Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Wright takes estrogen mainly to protect bone, muscle, brain and heart, not for hot flashes.
01:50:31Dr. Vonda Wright · The Diary of a CEO · Jul 2024
Spector reveals his 93-year-old mother June has dementia and no longer recognizes him, motivating his brain research.
00:02:35Tim Spector · The Diary of a CEO · Jan 2026
Claims that for 40 years medicine went down the wrong path obsessing over serotonin and dopamine while missing inflammation and metabolism.
00:18:44Tim Spector · The Diary of a CEO · Jan 2026
States about 90% of people who develop Parkinson's had gut problems 10 years earlier, suggesting the disease starts in the gut.
00:21:50Tim Spector · The Diary of a CEO · Jan 2026
His new trial found a prebiotic (Daily 30) changed ~40 gut microbes versus only 4-5 for a probiotic, reversing his view on which is more powerful.
00:34:27Tim Spector · The Diary of a CEO · Jan 2026
The USDA recently reversed decades of guidance, now saying fat is good and past low-fat advice was wrong.
00:50:36Tim Spector · The Diary of a CEO · Jan 2026
In a 100,000-person time-restricted eating study, a third quit, a third loved it, and a third did it sometimes.
01:09:55Tim Spector · The Diary of a CEO · Jan 2026
Spector found he is in the highest 20% for blood microplastics, likely from decades cycling in London.
01:20:21Tim Spector · The Diary of a CEO · Jan 2026
GLP-1 drugs appear brain-protective and reduce dementia risk, but he worries they may dampen the risk-taking drives that make good entrepreneurs.
01:24:32Tim Spector · The Diary of a CEO · Jan 2026
Flossing properly can roughly halve your risk of dementia by reducing harmful oral bacteria.
00:00:00Tim Spector · The Diary of a CEO · Jan 2026
The vagus nerve is the body's longest nerve and 80% of its signals travel from gut to brain, only 20% brain to gut.
00:10:55Tim Spector · The Diary of a CEO · Jan 2026
Drinking two to five cups of coffee a day reduces heart disease risk by about 25%.
00:01:02Tim Spector · The Diary of a CEO · Jan 2026
There are 40-100 trillion gut microbes; one species, Lawsonibacter, only feeds on coffee.
00:25:59Tim Spector · The Diary of a CEO · Jan 2026
The gut's enteric nervous system is our 'second brain' and was actually the first brain formed in the embryo.
00:38:39Tim Spector · The Diary of a CEO · Jan 2026
About 70% of our immune cells live in the gut, mostly in the large intestine.
00:39:11Tim Spector · The Diary of a CEO · Jan 2026
A Stanford study showed five portions of fermented foods a day cut blood inflammation by about 25% in a month.
00:48:32Tim Spector · The Diary of a CEO · Jan 2026
Up to 30% of people think gluten is a problem for them, but only about 1% actually need to avoid it.
01:03:35Tim Spector · The Diary of a CEO · Jan 2026
Ultra-processed foods make you overeat by roughly 25% because they are hyper-palatable and barely need chewing.
01:00:28Tim Spector · The Diary of a CEO · Jan 2026
After about two days without food the brain switches from glucose to ketones, a reset still used to treat drug-resistant childhood epilepsy.
01:13:01Tim Spector · The Diary of a CEO · Jan 2026
States flatly there is no credible evidence seed oils are harmful — they are actually beneficial.
00:00:00Dr Sarah Berry · The Diary of a CEO · Jan 2025
Discloses her almond snack study was funded by the Almond Board of California, while defending its independence.
00:32:21Dr Sarah Berry · The Diary of a CEO · Jan 2025
Explains the Sydney Diet Heart Study against seed oils is flawed because the oils then contained harmful trans fats.
01:08:48Dr Sarah Berry · The Diary of a CEO · Jan 2025
Coins 'menowashing' — slap 'meno' on any product and charge 10x; holds up Yorkshire Tea as the joke example.
01:44:58Dr Sarah Berry · The Diary of a CEO · Jan 2025
Says soy isoflavones are the only supplement with even weak evidence for menopause symptoms.
01:54:15Dr Sarah Berry · The Diary of a CEO · Jan 2025
Defends scientists working with the food industry, arguing the anti-industry narrative is creating a climate of fear.
01:59:28Dr Sarah Berry · The Diary of a CEO · Jan 2025
Reveals her proudest achievement is the four years she spent caring for her dying mother, not becoming a professor.
02:04:40Dr Sarah Berry · The Diary of a CEO · Jan 2025
Changing your eating speed by 20% cuts calorie intake by about 15%.
00:01:01Dr Sarah Berry · The Diary of a CEO · Jan 2025
You excrete 20-30% of the calories from whole nuts because intact cell walls trap the fat undigested.
00:21:50Dr Sarah Berry · The Diary of a CEO · Jan 2025
Finely ground oats produce roughly a 50% higher blood-glucose response than coarse oats with identical nutrients.
00:25:32Dr Sarah Berry · The Diary of a CEO · Jan 2025
Swapping 20% of energy from typical UK snacks to almonds improved blood vessel function equal to a 30% drop in cardiovascular disease in six weeks.
00:29:44Dr Sarah Berry · The Diary of a CEO · Jan 2025
About 25% of UK and US energy comes from snacks, and roughly 75% of those snacks are unhealthy.
00:32:52Dr Sarah Berry · The Diary of a CEO · Jan 2025
30% of people snack after 9pm, which is linked to more belly fat and inflammation even with healthy snacks.
00:37:36Dr Sarah Berry · The Diary of a CEO · Jan 2025
Cheese does not raise cholesterol but butter does, despite near-identical fat composition — due to the food matrix.
01:31:20Dr Sarah Berry · The Diary of a CEO · Jan 2025
Postmenopausal women have a fivefold higher risk of heart attack and their LDL cholesterol rises about 25%.
01:40:17Dr Sarah Berry · The Diary of a CEO · Jan 2025
Hot flushes affect only about 40% of women, while around 85% report brain fog — the opposite of public perception.
01:43:25Dr Sarah Berry · The Diary of a CEO · Jan 2025
In China people eat ~70mg of soy isoflavones a day versus ~1mg in the UK/US, tracking with lower menopause symptoms.
01:54:46Dr Sarah Berry · The Diary of a CEO · Jan 2025
Says by the end of 2021, crippled by chronic pain, she thought 'if this doesn't get better, I think I'm going to kill myself.'
00:00:46Dr. Tina Moore · The Diary of a CEO · Jul 2024
Reveals she missed her own mother's Crohn's disease for years and still carries guilt over it.
00:15:08Dr. Tina Moore · The Diary of a CEO · Jul 2024
Describes microdosing her own GLP-1 and feeling brain fog and anxiety lift within days.
00:35:57Dr. Tina Moore · The Diary of a CEO · Jul 2024
Cites the Novo Nordisk-funded SELECT trial showing a 20% reduction in major cardiovascular events.
00:43:42Dr. Tina Moore · The Diary of a CEO · Jul 2024
Notes SELECT data re-analysis found cardiovascular benefits occurred even in people who didn't lose weight.
00:55:36Dr. Tina Moore · The Diary of a CEO · Jul 2024
Demonstrates that standard dosing 10x's the dose over 16 weeks, which she calls unnecessary and high-risk.
01:13:42Dr. Tina Moore · The Diary of a CEO · Jul 2024
Claims by the mid-2040s sperm rates are projected to hit zero and frames metabolic dysfunction as the driver.
01:01:13Dr. Tina Moore · The Diary of a CEO · Jul 2024
Argues the Women's Health Initiative wrongly scared a generation of women off hormone therapy.
01:36:27Dr. Tina Moore · The Diary of a CEO · Jul 2024
GLP-1 receptors exist throughout the body and the drug is described as inducing neuroplasticity and neuron regeneration.
00:42:09Dr. Tina Moore · The Diary of a CEO · Jul 2024
She cites data on pancreatic beta-cell regeneration in type 1 diabetics if treated early enough.
00:44:43Dr. Tina Moore · The Diary of a CEO · Jul 2024
A chronic kidney disease (FLOW) trial was reportedly stopped early because the drug was so effective.
00:45:48Dr. Tina Moore · The Diary of a CEO · Jul 2024
A 2024 study (Lindsey Wang) found diabetics on Ozempic were 50% less likely to develop bowel cancer than those on insulin.
00:51:57Dr. Tina Moore · The Diary of a CEO · Jul 2024
2018 US data showed only 6.8% of US adults are metabolically healthy.
01:02:15Dr. Tina Moore · The Diary of a CEO · Jul 2024
In rat studies, semaglutide stopped rats seeking 'pleasure food' while they kept eating standard chow.
01:23:05Dr. Tina Moore · The Diary of a CEO · Jul 2024
A 186-person type 2 diabetes study found the strength-training-only group lost the most fat and most improved insulin resistance.
01:42:41Dr. Tina Moore · The Diary of a CEO · Jul 2024
Sauna-induced heat shock proteins are linked to roughly a 40% reduction in pneumonia risk.
01:48:17Dr. Tina Moore · The Diary of a CEO · Jul 2024
GLP-1 is produced in regions of the brain itself, not only the gut, with receptors all over the brain.
01:21:01Dr. Tina Moore · The Diary of a CEO · Jul 2024
As a child her ADHD ('hyperkinetic') prescription was a dog, constant physical activity, and avoiding 'white foods.'
01:50:22Dr. Tina Moore · The Diary of a CEO · Jul 2024
Calorie counting is 'complete nonsense' with no long-term study showing it sustains weight loss; over 95% of dieters regain the weight.
00:18:32Tim Spector · The Diary of a CEO · Jan 2023
Most vitamins and supplements are a waste of money, and calcium tablets may raise heart-disease risk.
00:40:46Tim Spector · The Diary of a CEO · Jan 2023
Exercise has very little role in weight loss; the link was exaggerated, partly funded by food and drink companies.
01:02:59Tim Spector · The Diary of a CEO · Jan 2023
Most people who believe they are gluten intolerant test fine; only ~1% have true celiac disease.
00:59:55Tim Spector · The Diary of a CEO · Jan 2023
Switching from sugary sodas to diet versions shows no real difference in weight; artificial sweeteners disrupt gut microbes and can spike blood sugar.
01:07:07Tim Spector · The Diary of a CEO · Jan 2023
One in four people eating an identical muffin get a blood-sugar dip and then overeat, disproving calories-in-calories-out.
00:23:11Tim Spector · The Diary of a CEO · Jan 2023
A Mediterranean gut-friendly diet produced better remission of depression than antidepressant medication in studies.
01:13:50Tim Spector · The Diary of a CEO · Jan 2023
The gut microbiome weighs roughly the same as the human brain, several pounds combined.
00:10:47Tim Spector · The Diary of a CEO · Jan 2023
In the UK, 24% of people carry the parasite Blastocystis, which is actually linked to good health and being thinner.
00:15:27Tim Spector · The Diary of a CEO · Jan 2023
Eating 30 different types of plant per week maximizes gut-microbe diversity; a plant includes nuts, seeds, herbs, spices and coffee.
00:16:29Tim Spector · The Diary of a CEO · Jan 2023
Ground almonds yield about 30% more available calories than whole almonds despite identical labeling.
00:23:42Tim Spector · The Diary of a CEO · Jan 2023
Iron added to some breakfast cereals can be pulled out with a magnet as iron filings and barely absorbs into the body.
00:29:54Tim Spector · The Diary of a CEO · Jan 2023
White chocolate is about 60% sugar.
00:51:36Tim Spector · The Diary of a CEO · Jan 2023
A ZOE time-restricted-eating study had 130,000 sign-ups; participants reported better mood, energy and reduced hunger.
00:36:04Tim Spector · The Diary of a CEO · Jan 2023
Transplanting gut bacteria from anxious mice into sterile mice makes the recipients anxious and depressed.
01:11:45Tim Spector · The Diary of a CEO · Jan 2023
UK children get over 70% of their food from ultra-processed sources; adults 50-60%.
01:18:31Tim Spector · The Diary of a CEO · Jan 2023
ZOE reached a roughly 200 million valuation with around a quarter-million people on its UK wait list.
01:23:41Tim Spector · The Diary of a CEO · Jan 2023
His father died by suicide, an event that first made Professor Green aware of the phrase mental health.
00:01:38Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
Multiple elders carried trauma: his father was in care, his twin died at birth, and his uncle also took his own life two years before his dad did.
00:16:42Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
He recounts his last conversation with his father, who threatened to knock him out, and says he does not regret his angry words.
00:46:12Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
He was stabbed in the neck with a broken bottle outside a club after standing his ground in a minor dispute.
01:02:45Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
He was legally pressured to testify against his attacker or be arrested, a conflict that still troubles him.
01:08:27Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
After a 2017 hiatus hernia operation he nearly died from complications and turned to holistic gut-health approaches.
01:23:28Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
He admits he believed becoming a successful musician would absolve his past and make him happy, and found it was bullshit.
01:15:43Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
His mother was 16 and his father 18 when he was born; they separated quickly.
00:07:24Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
He was born with pyloric stenosis and had an operation at six weeks old, later diagnosed with IBS, linking gut and brain.
00:11:32Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
He went from being offered a grammar-school exam at 11 to a pupil referral unit by 13, mainly due to attendance.
00:14:40Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
Professor Green did not sell his first record until age 28, after about ten years of pursuing music.
00:26:32Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
Bartlett spent six months working at a London psychedelics mental-health company.
00:35:23Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
Professor Green was hit and squashed between two cars in 2013, which he found more traumatic than being stabbed.
01:01:43Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
He made it as a white male in the UK hip-hop scene, which he and Bartlett note was a rare accomplishment.
01:13:37Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
He lost over a million pounds in endorsements after a 2013 arrest for something he was never charged with.
01:12:35Professor Green (Stephen Manderson) · The Diary of a CEO · May 2021
Li says he has now 'seen where the end of cancer is coming from' and has had over a dozen patients go from stage 4 to stage 0.
00:06:43Dr. William Li · The Diary of a CEO · May 2025
His own mother went from stage 4 endometrial cancer to stage zero after just three immunotherapy treatments, with no chemotherapy, and is healthy at 90+.
01:00:07Dr. William Li · The Diary of a CEO · May 2025
Discloses a seven-figure personal investment into a matcha company a couple of years ago.
00:43:30Dr. William Li · The Diary of a CEO · May 2025
A study found men with microplastics embedded in their carotid artery had a four-fold (400%) increase in fatal heart attack or stroke risk.
00:35:46Dr. William Li · The Diary of a CEO · May 2025

What Diary of a CEO says about gut health

In their own words

What Diary of a CEO recommends for gut health

Creatine Monohydrate

Creatine

Why We Sleep

Lost Connections

Vitamin D3

Akkermansia muciniphila probiotic

Lactobacillus reuteri probiotic